Another approach to in vivo estimation of genetic damage in humans.
نویسندگان
چکیده
Direct measurements of the genetic hazards to man have been determined previously by the appearance of elevated in vivo levels of chromosome aberrations. Here we report that interindividual variations in N-acetoxy-2-acetyl-aminofluorene-induced unscheduled DNA synthesis values parallel the actual in vivo levels of chromosome damage and, therefore, may be a rapid useful supplement in genetic risk assessment for humans.
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ورودعنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 76 1 شماره
صفحات -
تاریخ انتشار 1979